Cortical data/

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Validation Data for Cortical Reconstruction Algorithms

This validation data set contains volumetric T1 and FLAIR MR images of five healthy volunteers and five MS subjects. It also includes manually picked landmark points in seven different regions of the cortex on both inner and outer surfaces. The MS subjects have additional landmarks, picked in the vicinity of white matter lesions.


Data Information

Modality  Resolution 
Healthy Volunteers (HV) T1 (MPRAGE) 1.0 x 1.0 x 1.0 millimeters
FLAIR 1.0 x 1.0 x 1.0 millimeters
Multiple Sclerosis (MS) T1 (MPRAGE) 0.83 x 0.83 x 0.83 millimeters
FLAIR 0.83 x 0.83 x 0.83 millimeters


Data Layout

JHU_cortical_validation_data-v1.2
 |
 |- landamrks
 |   |
 |   |- Rater_A
 |   |   |
 |   |   |- JHU_cortical_landmarks_HV1_RaterA_LCALC_GC.xml
 .   .   .                   .
 .   .   .                   .
 |   |   \- JHU_cortical_landmarks_MS5_RaterA_RSYL_GW.xml
 |   |
 |   |- Rater_B
 |   |   |
 |   |   |- JHU_cortical_landmarks_HV1_RaterB_LCALC_GC.xml
 .   .   .                   .
 .   .   .                   .
 |   |   \- JHU_cortical_landmarks_MS5_RaterB_RSYL_GW.xml
 |   |
 |   \- Rater_C
 |       |
 |       |- JHU_cortical_landmarks_MS1_RaterC_lesion_GC.xml
 .       .                   .
 .       .                   .
 |       \- JHU_cortical_landmarks_MS5_RaterC_lesion_GW.xml
 |
 \- volumetric_images
     |
     |- JHU_cortical_validation_HV1_FLAIR.nii
     |- JHU_cortical_validation_HV1_T1.nii
     .               .
     .               .
     |- JHU_cortical_validation_HV5_FLAIR.nii
     |- JHU_cortical_validation_HV5_T1.nii
     |- JHU_cortical_validation_MS1_FLAIR.nii
     |- JHU_cortical_validation_MS1_T1.nii
     .               .
     .               .
     |- JHU_cortical_validation_MS5_FLAIR.nii
     \- JHU_cortical_validation_MS5_T1.nii


Data Download

Download the data. Any work that uses this data should cite:

  • N.Shiee, P.-L. Bazin, J.L. Cuzzocreo, C. Ye, B. Kishore, A. Carass, P.A. Calabresi, D.S. Reich, J.L. Prince, and D.L. Pham, "Robust Reconstruction of the Human Brain Cortex in the Presence of the WM Lesions: Method and Validation", Human Brain Mapping, 35(7):3385-3401, 2014. (doi)