Xiaofeng Liu

1136 D Regina Dr * Baltimore, MD 21227 * Phone: 410-322-1719 * Email: xiaofeng.liu@gmail.com

RESEARCH

EXPERTISE

Medical image analysis, magnetic resonance imaging, motion analysis, vector spline interpolation, image registration, computer aided diagnosis and image-guided surgery, tomosynthesis, image segmentation, C-arm fluoroscopy, optical/magnetic tracking system.

 

EDUCATION

The Johns Hopkins University

Baltimore MD

PhD in Computer Science

Oct. 2009 (expected)

 

Vanderbilt University

Nashville TN

Master of Science in Computer Science

 

May 2003

Institute of Automation, Chinese Academy of Sciences

Beijing, China

Master of Engineering in Pattern Recognition & Artificial Intelligence

 

July 2001

University of Science and Technology of China

Hefei, China

Bachlor of Engineering in Automatic Control

July 1998

 

EXPERIENCE

 

Johns Hopkins University

Baltimore, MD

Research Assistant, advised by Dr. Jerry L. Prince

Sept. 2004 – present

-   Developed a method of 3D reconstruction of dense incompressible deformation field of the heart and the tongue using divergence-free vector spline.

-   Developed and implemented a system to quantify 3D tongue motion using zHARP.

-   Developed a method of 3D tongue motion tracking during speech using iterative method.

-   Developed a robust 2D HARP tracking refinement method based on single source shortest path concept.

-   Developed a robust 2D HARP tracking refinement method using seeded region growing.

-   Analyzed statistical property of 2D tongue velocity field using principal component analysis.

-   Developed a prostate brachytherapy seed reconstruction method using tomosynthesis and optimal coverage from X-ray fluoroscopy images.

-   Implemented and optimized a 3D nonrigid image registration algorithm using adaptive bases and applied it to brain volume registration. Delivered a software package that is being intensively used in both our lab and collaborating labs.

 

Siemens Corporate Research

Baltimore, MD

Intern, advised by Drs. Li Pan and Christine Lorenz

June 2006 – Sept.  2006

-   Determined theoretically the signal behavior of MR tagging using SSFP sequence.

-   Optimized and validated pulse sequence of strain encoding (SENC) imaging using SSFP.

 

Johns Hopkins University

Baltimore, MD

Research Assistant, advised by Dr. Russel H. Taylor

July 2003 – Aug. 2004

-   Characterized and corrected field distortion of electromagnetic tracking system (Aurora).

-   Developed a Polaris optical tracking system controller in Matlab.

-   Developed an image processing software in Matlab for computer assisted hip osteotomy surgery.

 

Vanderbilt University

Nashville, TN

Research Assistant, advised by Dr. J. Michael Fitzpatrick

Jan. 2002 – May 2003

-   Developed a method to identify and localize fiduacial markers from CT images for retrospective registration using optical flow,  and incorporated the marker orientation into fiducial registration. (This work was purchased by a company and is used on clinical application.)

 

NLPR, Chinese Academy of Sciences

Beijing, China

Research Assistant, advised by Dr. Hanqing Lu

July 1999 – June 2001

-   Constructed  a virtual bronchus endoscopy system.

-   Performed 3D pelvis segmentation from CT Images for pelvis reconstruction surgery.

 

PUBLICATION

 

Journal Papers

 

1.     J. Lee, X. Liu, A. K. Jain, E. C. Burdette, J. L. Prince, and G. Fitchinger, Prostate Brachytherapy Seed Reconstruction with Gaussian Blurring and Optimal Coverage Cost. IEEE Trans. Med. Imag.(Accepted)

2.     X. Liu, and J. L. Prince, "Shortest Path Refinement for Motion Estimation from Tagged MR Images". (Submitted to IEEE Trans. Med. Imag.)

3.     X. Liu, J. L. Prince, "Dense Three-dimensional Incompressible Motion Estimation of the Left Ventricle using Tagged MR Images". (In Preparation.)

Conference Papers

 

1.     M. Stone, X. Liu, H. Chen, J. L. Prince, "A Preliminary Application of Principal Component Analysis to Tongue Motion Patterns," 1st International Workshop on Dynamic Modeling of the Oral, Pharyngeal and Laryngeal Complex for Biomedical Applications, 2009. (To appear)

2.     X. Liu, J. L. Prince, "Incompressile Cardiac Motion Estimation of the Left Ventricle Using Tagged MR Images," the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2009.

3.     M. Stone, X. Liu, E. Murano, J. Zhuo, R. Gullapalli, A. Salama, and J. L. Prince, "Principal Component Analysis of Internal Tongue Motion in Normal and Glossectomy Patients with Primary Closure and Free Flap, " Proceeding of the International Symposium on Biomechanics, Healthcare and Information Science, 2009, Kanazawa, Japan.

4.     X. Liu, S. Roys, J. L. Prince and R. Gullapalli, "Landmark-based Prostate MR Image Matching Using Incompressible Large Deformation Diffeomorphism," Proceeding of ISMRM 2009 (Abstract) (To appear).

5.     X. Liu, J. Zhuo, H. Agarwal, K. Z. Abd-Elmoniem, E. Murano, M. Stone, R. Gullapalli, and J. L. Prince, "Quantification of Three Dimensional Tongue Motion During Speech Using zHARP, " Proceeding of SPIE Medical Imaging, 2009.

6.     X.  Liu, Y. Bai and J. L. Prince, "Shortest Path Refinement for HARP Motion Tracking," Proceeding of SPIE Medical Imaging 2009.

7.     J. Lee, X. Liu, J. L. Prince, G. Fitchinger, "Prostate Brachytherapy Seed Localization with Gaussian Blurring and Camera Self-Calibration," the 11th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2008.

8.     J. Lee, X. Liu, A. K. Jain, J. L. Prince, G. Fitchinger, "Tomosynthesis-based Radioactive Seed Localization in Prostate Brachytherapy Using Modified Distance Map Images," Proceeding of IEEE International Symposium on Biomedical Imaging (ISBI), 2008.

9.     K. Z. Abd-Elmoniem, M. Stuber, A. A. Youssef, T. Sasano, T. P. Abraham, X. Liu, S. Mullur, E-J. P. Vonken, M. R. Abraham, and J. L. Prince, "Direct Quantification of 3-D Myocaridal Principal Strain Orientations: A new Insight into Heart Regional Function," Proceeding of ISMRM 2008 (Abstract).

10.   X. Liu, J. Zhuo, H. Agarwal, K. Z. Abd-Elmoniem, E. Murano, M. Stone, J. L. Prince, "HARP MRI Techniques for Imaging Tongue Motion," Proceedings of the Fourth International Symposium on Biomechanics, Healthcare and Information Science, 2008, Kanazawa, Japan.

11.   M. Stone, X. Liu, S. Shinagawa, E. Murano, R. Gullapalli,  J. Zhuo, J. L. Prince, "Speech Patterns in a Muscular Hydrostat: Normal and Glossectomy Tongue Movement," Proceedings of the International Symposium on Biomechanics, Healthcare and Information Science, 2008, Kanazawa, Japan.

12.   E. Murano, M. Stone, J. Zhuo, X. Liu, R. Gullapalli, A. Salama, R. Ord, J. L. Prince, "Functional Outcomes of Glossectomy Surgery with and without Flap Reconstruction," Proceedings of the International Symposium on Biomechanics, Healthcare and Information Science, 2008, Kanazawa, Japan.

13.   X. Liu, A. K. Jain, G. Fitchtinger, "Prostate Implant Reconstruction with Discrete Tomography," the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2007.

14.   X. Liu, Jerry L. Prince, "Fast and Robust HARP Tracking Using Region Growing," Proceeding of ISMRM 2007 (Abstract).

15.   X. Liu, L. Pan, W. Relwald, and C. Lorenz, "Study of Magnetization Behavior of MR Tagging with Steady State Free Precession," Proceeding of ISMRM 2007 (Abstract).

16.   X. Liu, E. Murano, M. Stone, and J. L. Prince, "HARP Tracking Refinement Using Seeded Region Growing," Proceeding of IEEE International Symposium on Biomedical Imaging (ISBI) 2007.

17.   V. Parthasarathy, X. Liu, J. L. Prince, and M. Stone, "Three Dimensional Tracking of Tongue Motion Using Harmonic Phase (HARP) Processing of Tagged cine-MR Images," Proceeding of International Symposium on Biomechanics, Healthcare and Information Science, 2007 (Co-first author).

18.   X. Liu, M. stone, and J. L. Prince, "Tracking Tongue Motion in Three Dimensions Using Tagged MR Images," Proceeding of IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1372-1375 2006.

19.   R. Armiger, M. Armand, J. Lepisto, X. Liu, K. Tallroth, R. H. Taylor, "Three-Dimensional Biomechanical Analysis of Acetabular Osteotomy for Preoperative Planning," 5th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2005.

20.   M. Armand, R. Armiger, G. Chintalapani, X. Liu, R. Szczepanowski, S. Feng, D. Minhas R. Taylor, J. Lepist, "Computer-assisted Hip Osteotomy Surgery with Near Real-Time Biomechanical Feedback," 5th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2005.

21.   M. Armand, J. Lepisto, A. Merkle, K. Tallroth, X. Liu, R. H. Taylor, J. Wenz, "Computer-Aided Orthopedic Surgery with Near-Real-Time Biomechanical Feedback," Johns Hopkins APL Technical Digest 2004.

22.   X. Liu, H. Cevikalp, J. M. Fitzpatrick, "Marker Orientation in Fiducial Registration," SPIE Medical Imaging 2003, Proceedings of the SPIE, vol. 5032, pp. 1176-1185, 2003.

23.   X. Liu, H. Lu, "An Algorithm of Segmentation for Virtual Endoscopy," Proceedings of the SPIE, vol. 4550, pp. 24-27, 2001.

24.   X. Liu, X. Chang H. Lu, "Construction of a Virtual Bronchus Endoscopy System," Proceedings of the SPIE, vol. 4553, pp. 138-142,  2001.