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Learning from Multiple Experts with Random Forests: Application to the Segmentation of the Midbrain in 3D Ultrasound

Pierre Chatelain1, 2, Olivier Pauly1, 3, Loïc Peter1, Seyed-Ahmad Ahmadi1, Annika Plate4, Kai Bötzel4, and Nassir Navab1

1Computer Aided Medical Procedures, Technische Universität München, Germany
pierre.chatelain@cs.tum.edu

2Ecole Normale Supérieure de Cachan, Antenne de Bretagne, France

3Institute of Biomathematics and Biometry, Helmholtz Zentrum München, Germany

4Department of Neurology, Ludwig-Maximilians-Universität München, Germany

Abstract. In the field of computer aided medical image analysis, it is often difficult to obtain reliable ground truth for evaluating algorithms or supervising statistical learning procedures. In this paper we present a new method for training a classification forest from images labelled by variably performing experts, while simultaneously evaluating the performance of each expert. Our approach builds upon state-of-the-art randomized classification forest techniques for medical image segmentation and recent methods for the fusion of multiple expert decisions. By incorporating the performance evaluation within the training phase, we obtain a novel forest framework for learning from conflicting expert decisions, accounting for both inter- and intra-expert variability. We demonstrate on a synthetic example that our method allows to retrieve the correct segmentation among other incorrectly labelled images, and we present an application to the automatic segmentation of the midbrain in 3D transcranial ultrasound images.

LNCS 8150, p. 230 ff.

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