Andrew

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Andrew Lang

I am currently a Ph.D. student in the Electrical and Computer Engineering Department at Johns Hopkins University working in the Image Analysis and Communications Lab (IACL) under the supervision of Dr. Jerry Prince. My current research focuses on image analysis of retinal optical coherence tomography data.

Image Analysis and Communications Laboratory
Department of Electrical Engineering
Johns Hopkins University

Google Scholar Site

Education

MASc, Electrical and Computer Engineering, Queen's University, Kingston, ON, Canada, 2009
BS, Electrical and Computer Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, 2007

Experience

Research Assistant, Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, 2010-Present
Internship, MIT Lincoln Laboratory, Lexington, MA, Summer 2015
Internship, Philips Research North America, Briarcliff Manor, NY, 2009-2010
Research Assistant, Electrical and Computer Engineering, Queen's University, Kingston, ON, Canada, 2007-2009

Publications

Journal Articles

P. Bhargava, A. Lang, O. Al-Louzi, A. Carass, J. L. Prince, P. A. Calabresi, S. Saidha. “Applying an open-source segmentation algorithm to different OCT devices in Multiple Sclerosis patients and healthy controls: implications for clinical trials.” Multiple Sclerosis International, 2015, Article ID 136295, 10 pages, 2015. (doi)

A. Lang, A. Carass, E. K. Swingle, O. Al-Louzi, P. Bhargava, S. Saidha, H. S. Ying, P. A. Calabresi, J. L. Prince. “Automatic segmentation of microcystic macular edema in OCT.” Biomedical Optics Express 6(1), 155-169, 2015. (doi)

B. M. Jedynak, B. Liu, A. Lang, Y. Gel, J. L. Prince . “A computational method for computing an Alzheimer's Disease Progression Score; experiments and validation with the ADNI dataset.” Neurobiology of Aging 36(Supp. 1), S178-S184, 2015. (doi)

M. Bilgel, Y. An, A. Lang, J. Prince, L. Ferrucci, B. Jedynak, S. M. Resnick, “Trajectories of Alzheimer disease-related cognitive measures in a longitudinal sample.” Alzheimer’s & Dementia 10(6), 735–742.e4, 2014. (doi)

M. Chen, A. Lang, H. S. Ying, P. A. Calabresi, J. L. Prince, A. Carass. “Analysis of macular OCT images using deformable registration.” Biomedical Optics Express 5(7), 2196-2214, 2014. (doi)

A. Carass, A. Lang, M. Hauser, P. A. Calabresi, H. S. Ying, J. L. Prince. “Multiple-object geometric deformable model for segmentation of macular OCT.” Biomedical Optics Express 5(4), 1062-1074, 2014. (doi) (errata)

A. Lang, A. Carass, M. Hauser, E. S. Sotirchos, P. A. Calabresi, H. S. Ying, J. L. Prince. “Retinal layer segmentation of macular OCT images using boundary classification.” Biomedical Optics Express 4(7), 1133-1152, 2013. (doi)

C. R. Hatt, A. K. Jain, V. Parthasarathy, A. Lang, A. N. Raval. “MRI—3D ultrasound—X-ray image fusion with electromagnetic tracking for transendocardial therapeutic injections: In-vitro validation and in-vivo feasibility.” Computerized Medical Imaging and Graphics 37(2), 162-173, 2013. (doi)

B.M. Jedynak, A. Lang, B. Liu, E. Katz, Y. Zhang, B. T. Wyman, D. Raunig, C. P. Jedynak, B. Caffo, J. L. Prince. “A computational neurodegenerative disease progression score: Method and results with the Alzheimer's disease neuroimaging initiative cohort.” NeuroImage 63(3), 1478-1486, 2012. (doi)

A. Lang, P. Mousavi, S. Gill, G. Fichtinger, P. Abolmaesumi. “Multi-modal registration of speckle-tracked freehand 3-D ultrasound to CT in the lumbar spine.” Medical Image Analysis 16(3), 675-686, 2011. (doi)

Conference Papers

A. Lang, A. Carass, B. Jedynak, S. D. Solomon, P. A. Calabresi, J. L. Prince. “Intensity inhomogeneity correction of macular OCT using N3 and retinal flatspace.” International Symposium on Biomedical Imaging (ISBI'16), Prague, Czech Republic, April 2016. To Be Presented

A. Lang, A. Carass, O. Al-Louzi, P. Bharghava, S. D. Solomon, P. A. Calabresi, J. L. Prince. “Combined registration and motion correction of longitudinal retinal OCT data.” SPIE Medical Imaging, San Diego, CA, Feb. 2016. To Be Presented

B. J. Antony, A. Lang, E. K. Swingle, O. Al-Louzi, A. Carass, S. D. Solomon, P. A. Calabresi, S. Saidha, J. L. Prince. “Simultaneous segmentation of retinal surfaces and microcystic macular edema in SDOCT volumes,.” SPIE Medical Imaging, San Diego, CA, Feb. 2016. To Be Presented

A. Lang, A. Carass, O. Al-Louzi, P. Bharghava, H. S. Ying, P. A. Calabresi, J. L. Prince. “Longitudinal graph-based segmentation of macular OCT using fundus alignment.” Proc. SPIE Medical Imaging, 9413, 94130M, Orlando, FL, Feb. 2015. Oral Presentation (doi)

E. K. Swingle, A. Lang, A. Carass, O. Al-Louzi, J. L. Prince, P. A. Calabresi. “Segmentation of microcystic macular edema in Cirrus OCT scans with an exploratory longitudinal study.” Proc. SPIE Medical Imaging, 9417, 94170P, Orlando, FL, Feb. 2015. (doi)

A. Lang, A. Carass, P. A. Calabresi, H. S. Ying, J. L. Prince. “An adaptive grid for graph-based segmentation in retinal OCT.” Proc. SPIE Medical Imaging, 9034, 903402, San Diego, CA, Feb. 2014. Oral Presentation (doi)

E. K. Swingle, A. Lang, A. Carass, H. S. Ying, P. A. Calabresi, J. L. Prince. “Microcystic macular edema detection in retina OCT images.” Proc. SPIE Medical Imaging, 9038, 90380G, San Diego, CA, Feb. 2014. (doi)

M. Chen, A. Lang, E. Sotirchos, H. S. Ying, P. A. Calabresi, J. L. Prince, A. Carass. “Deformable registration of macular OCT using A-mode scan similarity.” Proc. 10th IEEE International Symposium on Biomedical Imaging (ISBI), 476-479, San Francisco, CA, April 2013. (doi)

A. Lang, A. Carass, E. Sotirchos, P. Calabresi, J. L. Prince. “Segmentation of retinal OCT images using a random forest classifier.” Proc. SPIE Medical Imaging, 8669, 86690R, Lake Buena Vista, FL, Feb. 2013. Oral Presentation (doi)

A. Lang, V. Parthasarathy and A. Jain, “Calibration of 3D ultrasound to an electromagnetic tracking system”, Proc. SPIE Medical Imaging, 7968, 79680W, Lake Buena Vista, FL, Feb. 2011. (doi)

A. Lang, D. Stanton, V. Parthasarathy, A. Jain. “Fast and accurate calibration of an X-ray imager to an electromagnetic tracking system for interventional cardiac procedures.” Proc. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 1868-1873, Buenos Aires, Argentina, Sept. 2010. (doi)

A. Lang, P. Mousavi, G. Fichtinger, P. Abolmaesumi. “Fusion of electromagnetic tracking with speckle-tracked 3D freehand ultrasound using an unscented Kalman filter.” Proc. SPIE Medical Imaging, 7265, 72651A, Lake Buena Vista, FL, Feb. 2009. (doi)

Conference Abstracts

O. Al-Louzi, J. Button, A. Lang, P. Bhargava, S. Newsome, A. Carass, L. Balcer, E. Frohman, J. Prince, P. Calabresi, S. Saidha. “Disease modifying therapies modulate retinal layer atrophy in multiple sclerosis: a longitudinal study.” 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRMS 2015), Barcelona, Spain, Oct. 2015.

A. Lang, A. Carass, A. Bittner, J. Prince, H. Ying. “Automated segmentation of eight layers in 3D SD-OCT scans of retinitis pigmentosa patients and the relationship of GCL+IPL thickness to visual function.” ARVO 2015 Annual Meeting, Association for Research in Vision and Ophthalmology, Denver, CO, May 2015.

O. Al-Louzi, A. Lang, P. Bhargava, A. Carass, J. Prince, S. Saidha, P. Calabresi. “Fingolimod therapy in multiple sclerosis is associated with an increase in inner nuclear layer.” Neuroscience 2014, Society for Neuroscience, Washington DC, Nov. 2014. (link)

P. Bhargava, A. Lang, O. Al-Louzi, A. Carass, S. Saidha, J. Prince, P. A. Calabresi. “Cross-platform comparison of retinal layers in multiple sclerosis utilizing a novel open-source optical coherence tomography automated segmentation algorithm.” 2014 Cooperative Meeting of CMSC and ACTRIMS, Dallas, TX, May 2014. (doi)

P. Bhargava, A. Lang, O. Al-Louzi, A. Carass, S. Saidha, J. Prince, P. Calabresi. “Cross-Platform Comparison of Retinal Neuronal Layers in Multiple Sclerosis Utilizing a Novel Open-Source Optical Coherence Tomography Automated Segmentation Algorithm.” AAN Annual Meeting 2014, American Academy of Neurology, Philadelphia, PA, April 2014. (link)

B. Jedynak, Z. Ye, A. Lang, R. Tang, C. P. Jedynak and J. Prince. "The Alzheimer's Disease Progression Score (ADPS) can predict the transition from MCI to AD.” Alzheimer's Association International Conference 2013, Alzheimer's Association, Boston, MA, July 2013.

M. Bilgel, Y. An, A. Lang, J. Prince, B. Jedynak, S. M. Resnick. “Temporal Sequence of Alzheimer's Disease-Related Cognitive Biomarker Changes in the Baltimore Longitudinal Study of Aging.” Alzheimer's Association International Conference 2013. Alzheimer's Association, Boston, MA, July 2013.

B. M. Jedynak. B. Liu, A. Lang, Y. Gel, J. L. Prince. “A time-change method for computing an Alzheimer’s disease progression score.” MICCAI 2012 Workshop on Novel Imaging Biomarkers for Alzheimer's Disease and Related Disorders (NIBAD'12). Nice, France, Oct. 2012.

B. M. Jedynak, A. Lang, B. Liu, B. Caffo, J. L. Prince, B. Wyman, Y. Zhang. “Modeling the progression of Alzheimer’s disease (AD) using the Alzheimer’s disease neuroimaging initiative (ADNI) cohort.” JSM Proceedings. American Statistical Association, San Diego, CA, July 2012.

A. Lang, B. Liu, B. Wyman, B. Caffo, Y. Zhang, E. Katz, P. Jedynak, J. L. Prince, B. M. Jedynak. “Time-dependent changes of 9 biomarkers related to Alzheimer’s disease.” Alzheimer's Association International Conference 2012. Alzheimer’s Association, Vancouver, BC, Canada, July 2012. Oral Presentation

B. M. Jedynak, B. Liu, A. Lang, B. Caffo, B. Wyman, E. Katz, Y. Zhang, C. P. Jedynak, J. L. Prince. “Sample size comparisons in ADNI: A case for the Alzheimer’s Disease Progression Scale.” Alzheimer's Association International Conference 2012. Alzheimer’s Association, Vancouver, BC, Canada, July 2012.

B. M. Jedynak, A. Lang, B. Liu, B. S. Caffo, C. P. Jedynak, J. L. Prince. “Standardizing AD progression using multiple biomarkers.” Neuroscience 2011, Society for Neuroscience, Washington DC, Nov. 2011.

Book chapter

A. Lang, V. Parthasarathy, A. Jain. “Calibration of EM Sensors for Spatial Tracking of 3D Ultrasound Probes.” Data Acquisition Applications. Zdravko Karakehayov (Ed.), Ch. 10, 253-268, InTech, 2012. (doi)

Thesis

A. Lang. “Improvement of Speckle-Tracked Freehand 3-D Ultrasound Through the Use of Sensor Fusion”, Queen’s University, Master of Applied Science Thesis, October 2009. (link)