Difference between revisions of "StatsWAP2009July17"

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(New page: <meta name="title" content="July 17, 2009"/> {{h2| Mixed Effects Models in MRI Research}} ''Summer Seminar Series:'' '''Statistics without the Agonizing Pain (WAP Series)''' <br>''Time/Lo...)
 
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<li> REML - restricted maximum likelihood -- preferred for model estimation. ''Not'' suitable for model comparison with differing random effects.  
 
<li> REML - restricted maximum likelihood -- preferred for model estimation. ''Not'' suitable for model comparison with differing random effects.  
 
<li> Empirical Bayes (EB) for estimation of individual trajectories
 
<li> Empirical Bayes (EB) for estimation of individual trajectories
<li>  
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<p> <h2>Links about R<h2>
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<li>''Fitting Linear Mixed Models in R'' : http://cran.osmirror.nl/doc/Rnews/Rnews_2005-1.pdf#page=27
 
</ul>
 
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<p> Generalized estimating equations (discontinuous outcomes)
 
<p> Generalized estimating equations (discontinuous outcomes)

Revision as of 19:30, 17 July 2009

<meta name="title" content="July 17, 2009"/>

Mixed Effects Models in MRI Research

Summer Seminar Series: Statistics without the Agonizing Pain (WAP Series)
Time/Location: Friday, July 17, 2009 – 3 pm – 4 pm Clark Hall 314
Speaker: Yang An, National Institute on Aging - Intramural Research Program

Laboratory of Personality and Cognition - http://www.grc.nia.nih.gov/branches/lpc/lpc.htmv
Cognition section - http://www.grc.nia.nih.gov/branches/lpc/sresnick.htm

Mixed effects models (continuous outcomes) - also known as random effects models

General topics

  • Ordinary regression model - each data point comes from a separate "person" - L2 fit - Fixed effects
  • ME model - each subject has its own slope. Find population slope.
  • REML - restricted maximum likelihood -- preferred for model estimation. Not suitable for model comparison with differing random effects.
  • Empirical Bayes (EB) for estimation of individual trajectories

Links about R

Generalized estimating equations (discontinuous outcomes)