Murat

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Murat Bilgel

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Image Analysis and Communications Laboratory, Johns Hopkins University
Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health

Contact Information

Johns Hopkins University
Clark Hall 204
3400 North Charles Street
Baltimore, MD 21218
Email: mbilgel1@jhmi.edu

Education

  • Ph.D., Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 2011 - Present
  • B.S., Biomedical Engineering, Johns Hopkins University School of Engineering, Baltimore, MD, 2007 - 2011
  • IB Diploma, Armand Hammer United World College of the American West, Montezuma, NM, 2005 - 2007

Honors and Awards

  • Pre-doctoral Intramural Research Training Award, National Institutes of Health, Fall 2012 - Present
  • Fellows Award for Research Excellence, National Institutes of Health, Summer 2015
  • Alzheimer's Association International Conference Travel Fellowship, Summer 2015
  • Human Amyloid Imaging Young Investigator Travel Scholarship, Winter 2014-5
  • Graduate Student Association Travel Award, Johns Hopkins University School of Medicine, Spring 2013
  • Member, Tau Beta Pi National Engineering Honor Society
  • Richard J. Jones Award For Outstanding Academic Achievement, Johns Hopkins University School of Engineering, Spring 2011

Publications

Journal Articles

  • S. Roy, A. Carass, J. Pacheco, M.Bilgel, S. M. Resnick, J. L. Prince, D. L. Pham, "Temporal filtering of longitudinal brain magnetic resonance images for consistent segmentation", NeuroImage: Clinical, [in press].
  • M.Bilgel, Y. An, Y. Zhou, D. F. Wong, J. L. Prince, L. Ferrucci, S. M. Resnick, "Individual estimates of age at detectable amyloid onset for risk factor assessment", Alzheimer's & Dementia, [in press].
  • M. Thambisetty, Y. Chuang, Y. An, M. Bilgel, D. Wong, J. Troncoso, R. O'Brien, J. Breitner, L. Ferrucci, S. Resnick, "Midlife adiposity predicts earlier onset of Alzheimer's dementia, neuropathology and presymptomatic cerebral amyloid accumulation", Molecular Psychiatry, [epub ahead of print]. (doi)
  • M. Bilgel, A. Carass, S. M. Resnick, D. F. Wong, J. L. Prince, "Deformation field correction for spatial normalization of PET images", NeuroImage, 119(1):152-163, October 2015. (doi)
  • J. Sojkova, J. Goh, M. Bilgel, B. Landman, X. Yang, Y. Zhou, Y. An, L. L. Beason-Held, M. A. Kraut, D. F. Wong, S. M. Resnick, "Voxel-wise relationships between distribution volume ratio and cerebral blood flow: implications for analysis of β-amyloid images", Journal of Nuclear Medicine, 56(7):1042-1047, July 2015. (doi)
  • S. M. Resnick, M. Bilgel, A. Moghekar, A. Yang, Q. Cai, M. Wang, M. Thambisetty, J. L. Prince, Y. Zhou, A. Soldan, D. F. Wong, R. J. O'Brien, L. Ferrucci, M. S. Albert, "Changes in Aβ biomarkers and associations with APOE genotype in two longitudinal cohorts", Neurobiology of Aging, 36(8):2333-2339, August 2014. (doi)
  • P. A. Nyquist, M. Bilgel, R. Gottesman, L. R. Yanek, T. F. Moy, L. C. Becker, J. L. Cuzzocreo, J. Prince, B. A. Wasserman, D. M. Yousem, D. M. Becker, B. G. Kral, D. Vaidya, "Age differences in periventricular and deep white matter lesions", Neurobiology of Aging, 36(4):1653-1658, April 2015. (doi)
  • P. A. Nyquist, L. R. Yanek, M. Bilgel, J. Cuzzocreo, L. C. Becker, K. Chevalier-Davis, D. Yousem, J. Prince, B. G. Kral, D. Vaidya, D. M. Becker, "Effect of white matter lesions on manual dexterity in healthy middle-aged persons", Neurology, 84(19):1920-1926, May 2015. (doi)
  • M. Bilgel, Y. An, A. Lang, J. Prince, L. Ferrucci, B. Jedynak, S. M. Resnick, "Trajectories of Alzheimer disease-related cognitive measures in a longitudinal sample", Alzheimer’s & Dementia, 10(6):735-742, November 2014. (doi)
  • N. Annaluru, H. Muller, L. A. Mitchell, S. Ramalingam, G. Stracquadanio, S. M. Richardson, J. S. Dymond, Z. Kuang, L. Z. Scheifele, E. M. Cooper, Y. Cai, K. Zeller, N. Agmon, J. S. Han, M. Hadjithomas, J. Tullman, K. Caravelli, K. Cirelli, Z. Guo, V. London, A. Yeluru, S. Murugan, K. Kandavelou, N. Agier, G. Fischer, K. Yang, J. A. Martin, M. Bilgel, P. Bohutski, K. M. Boulier, B. J. Capaldo, J. Chang, K. Charoen, W. J. Choi, P. Deng, J. E. DiCarlo, J. Doong, J. Dunn, J. I. Feinberg, C. Fernandez, C. E. Floria, D. Gladowski, P. Hadidi, I. Ishizuka, J. Jabbari, C. Y. L. Lau, P. A. Lee, S. Li, D. Lin, M. E. Linder, J. Ling, J. Liu, J. Liu, M. London, H. Ma, J. Mao, J. E. McDade, A. McMillan, A. M. Moore, W. C. Oh, Y. Ouyang, R. Patel, M. Paul, L. C. Paulsen, J. Qiu, A. Rhee, M. G. Rubashkin, I. Y. Soh, N. E. Sotuyo, V. Srinivas, A. Suarez, A. Wong, R. Wong, W. R. Xie, Y. Xu, A. T. Yu, R. Koszul, J. S. Bader, J. D. Boeke, S. Chandrasegaran, "Total synthesis of a functional designer eukaryotic chromosome", Science, 344(6179):55-58, 4 April 2014. (doi)
  • P. A. Nyquist, M. Bilgel, R. Gottesman, L. R. Yanek, T. F. Moy, L. C. Becker, J. Cuzzocreo, J. Prince, D. M. Yousem, D. M. Becker, B. G. Kral, D. Vaidya, "Extreme deep white matter hyperintensity volumes are associated with African American race", Cerebrovasc. Dis., 37(4):244-250, Mar 2014. (doi)
  • A. P. Spira, A. A. Gamaldo, Y. An, M. N. Wu, E. M. Simonsick, M. Bilgel, Y. Zhou, D. F. Wong, L. Ferrucci, S. M. Resnick, "Self-reported Sleep and β-Amyloid Deposition in Community-Dwelling Older Adults", JAMA Neurology, 70(12):1537-1543, December 2013. (doi)

Conference Papers

  • M. Bilgel, B. Jedynak, D. F. Wong, S. M. Resnick, J. L. Prince, "Temporal trajectory and progression score estimation from voxelwise longitudinal imaging measures: Application to amyloid imaging", Information Processing in Medical Imaging (IPMI 2015), Isle of Skye, Scotland, June 28-July 3, 2015. (doi)
  • M. Bilgel, A. Carass, S. M. Resnick, D. F. Wong, J. L. Prince, "Deformation Field Correction for Spatial Normalization of PET Images Using a Population-Derived Partial Least Squares Model", Machine Learning in Medical Imaging (MLMI 2014), Boston, MA, September 14, 2014. (doi)
  • M. Bilgel, S. Roy, A. Carass, P. A. Nyquist, J. L. Prince, "Automated Anatomical Labeling of Cerebrovascular Networks", Proceedings of SPIE Medical Imaging (SPIE-MI 2013), Orlando, FL, February 9-14, 2013. (doi) Oral presentation.

Conference Abstracts

  • M. Bilgel, Y. An, Y. Zhou, D. F. Wong, J. L. Prince, S. M. Resnick, "Age at onset of amyloid accumulation in relation to APOE genotype", Alzheimer’s Association International Conference (AAIC 2015), Washington, DC, July 19-23, 2015. Oral presentation.
  • C. A. Fredericks, V. E. Sturm, A. Hua, M. Bilgel, D. F. Wong, S. M. Resnick, W. W. Seeley, "Neuroticism increases with age in cognitively normal older adults who are PiB positive", American Academy of Neurology 67th Annual Meeting (AAN 2015), Washington, DC, April 18-25, 2015.
  • M. Bilgel, Y. An, Y. Zhou, D. F. Wong, J. Prince, S. M. Resnick, "APOE ε4 allele is associated with an earlier onset of amyloid deposition", Human Amyloid Imaging Conference (HAI 2015), Miami, FL, January 14-16, 2015. Oral presentation.
  • M. Bilgel, S. M. Resnick, D. F. Wong, B. Jedynak, J. Prince, "Temporal progression of cerebral amyloid deposition as measured by 11C-PiB PET imaging", Human Amyloid Imaging Conference (HAI 2015), Miami, FL, January 14-16, 2015.
  • P. A. Nyquist, M. Bilgel, L. R. Yanek, T. F. Moy, L. C. Becker, J. Cuzzocreo, D. M. Yousem, D. M. Becker, B. G. Kral, D. Vaidya, "Age Associated Atrophy is More Closely Correlated to Periventricular than Deep White Matter Disease", International Stroke Conference (ISC 2014), San Diego, CA, February 12-14, 2014.
  • P. A. Nyquist, L. R. Yanek, M. Bilgel, J. Cuzzocreo, L. C. Becker, K. Chevalier, T. Woessner, D. M. Becker, "Manipulative Dexterity is Associated with Occult White Matter Ischemic Lesions in Healthy Asymptomatic Persons at Increased Risk for Cardiovascular Disease", International Stroke Conference (ISC 2014), San Diego, CA, February 12-14, 2014.
  • P. A. Nyquist, C. Talbot, M. Bilgel, L. R. Yanek, L. C. Becker, J. Cuzzocreo, R. Mathias, A. Berger, C. Cheadle, D. M. Becker, "Increased Activation of Inflammatory Genes in Monocytes of Healthy People with Ischemic White Matter Disease", International Stroke Conference (ISC 2014), San Diego, CA, February 12-14, 2014.
  • M. Bilgel, Y. Chuang, Y. An, J. Prince, D. F. Wong, M. Thambisetty, S. M. Resnick, "Body mass index is associated with verbal episodic memory in cognitively normal older individuals with low fibrillar amyloid-beta measured by [11C]-PiB", Human Amyloid Imaging Conference (HAI 2014), Miami, FL, January 15-17, 2014.
  • S. M. Resnick, M. Bilgel, Y. An, M. Thambisetty, M. A. Kraut, Y. Zhou, D. F. Wong, "Longitudinal change in amyloid deposition, measured by PET and 11-C-PiB in nondemented older adults", American College of Neuropsychopharmacology (ACNP 2013), Hollywood, FL, December 8-12, 2013.
  • M. Bilgel, Y. An, A. Lang, J. Prince, B. Jedynak, S. M. Resnick, "Temporal Sequence of Alzheimer’s Disease-Related Cognitive Biomarker Changes in the Baltimore Longitudinal Study of Aging", Alzheimer’s Association International Conference (AAIC 2013), Boston, MA, July 13-18, 2013.
  • A. P. Spira, A. A. Gamaldo, Y. An, M. N. Wu, E. M. Simonsick, M. Bilgel, Y. Zhou, D. F. Wong, L. Ferrucci, S. M. Resnick, "Subjective Sleep Indices and Neuroimaging Evidence of β-Amyloid Deposition in Older Adults", 27th Annual Meeting of the Associated Professional Sleep Societies (SLEEP 2013), Baltimore, MD, June 1-5, 2013.
  • P. Nyquist, L. Yanek, D. Vaidya, R. Gottesman, B. Kral, M. Bilgel, J. Cuzzocreo, J. Prince, L. Becker, D. Becker, "Extreme White Matter Hyperintensity Volumes are More Prevalent in African Americans in a Cohort at Risk for Vascular Disease", American Academy of Neurology 65th Annual Meeting, San Diego, CA, March 16-23, 2013.
  • P. A. Nyquist, M. Bilgel, L. R. Yanek, T. F. Moy, B. G. Kral, D. M. Becker, L. C. Becker, D. Vaidya, "The Distribution of White Matter Hyperintensities by Age in Persons with Familial Cardiovascular Risk", International Stroke Conference (ISC 2013), Honolulu, HI, February 6-8, 2013. Moderated poster.
  • M. Bilgel, J. L. Cuzzocreo, L. C. Becker, D. M. Becker, J. L. Prince, P. A. Nyquist, "Spatial Characterization of Deep White Matter Hyperintensities Seen on Brain MR Images in Asymptomatic Persons with a Family History of Early-Onset Coronary Artery Disease", Johns Hopkins University School of Medicine 3rd Annual Cardiovascular Research Retreat, Baltimore, MD, June 1, 2012.



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